ABL800 FLEX blood gas analyzer

Offering you trusted results and greater operational efficiency

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  • Reliable results on 18 vital parameters
  • Spend less time in front of the analyzer with FLEXQ
  • Configured to meet your needs

Reliable, Efficient, Flexible

The ABL800 FLEX blood gas analyzer utilizes automation to deliver trusted results, while supporting operational efficiency.

Amidst pressures to optimize resources and personnel, equip and empower busy laboratory staff with:

  • Results you can trust
  • Improved workflow
  • A flexible partner to meet your needs
 
 

"Drop-n-Go" on the FLEXQ 

Fully automatic scanning, mixing, and aspiration of blood samples

 

Easy to operate screen

Intuitive interface with highly responsive tablet-like interaction

 

Additional clinical insight

Measure up to 18 critical parameters on one sample to support fast diagnosis

 

Autocheck

Supporting compliance with automatic QC

Parameters measured

Blood gases: 
pH

Potential of hydrogen

The degree of acidity or alkalinity of any liquid (including blood) is a function of its hydrogen ion concentration [H+], and pH is simply a way of expressing hydrogen ion activity. The relationship between pH and hydrogen ion concentration is described thus:

pH = -log aH+
where aH+ is hydrogen ion activity.

Low pH is associated with acidosis and high pH with alkalosis [1].

Read more

 

1. CLSI. Blood gas and pH analysis and related measurements; Approved Guidelines. CLSI document CA46-A2, 29, 8. Clinical and Laboratory Standards Institute, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2009.

, pCO2

Partial pressure of carbon dioxide

Carbon dioxide (CO2) is an acidic gas; the amount of CO2 in blood is largely controlled by the rate and depth of breathing or ventilation. pCO2 is the partial pressure of CO2 in blood. It is a measure of the pressure exerted by that small portion (~5 %) of total CO2 that remains in the gaseous state, dissolved in the blood plasma. pCO2 is the respiratory component of acid-base balance and reflects the adequacy of pulmonary ventilation. The severity of ventilator failure as well as the chronicity can be judged by the accompanying changes in acid-base status [1].

Read more

 

1. Higgins C. Parameters that reflect the carbon dioxide content of blood. www.acutecaretesting.org Oct 2008.

, pO2

Partial pressure of oxygen

The amount of oxygen in blood is controlled by many variables, e.g. ventilation/perfusion. pO2 is the partial pressure of oxygen in a gas phase in equilibrium with the blood. pO2 only reflects a small fraction (1 – 2 %) of total oxygen in blood that is dissolved in blood plasma [1]. The remaining 98 – 99 % of oxygen present in blood is bound to the hemoglobin in the erythrocytes. pO2 primarily reflects the oxygen uptake in the lungs. 

Read more

 

1. Wettstein R, Wilkins R. Interpretation of blood gases. In: Clinical assessment in respiratory care, 6th ed. St. Louis: Mosby, 2010.

Metabolites: 
cGlu

Glucose

Glucose, the most abundant carbohydrate in human metabolism, serves as the major intracellular energy source (see lactate). Glucose is derived principally from dietary carbohydrate, but it is also produced – primarily in the liver and kidneys – via the anabolic process of gluconeogenesis, and from the breakdown of glycogen (glycogenolysis). This endogenously produced glucose helps keep blood glucose concentration within normal limits, when dietary-derived glucose is not available, e.g. between meals or during periods of starvation.

Read more

, cLac

Lactate

Lactate, the anion that results from dissociation of lactic acid, is an intracellular metabolite of glucose. It is produced by skeletal muscle cells, red blood cells (erythrocytes), the brain, and other tissues during anaerobic energy production (glycolysis). Lactate is formed in the intracellular fluid from pyruvate; the reaction is catalyzed by the enzyme lactate dehydrogenase (LDH) [1].

 

1. Robergs RA, Ghiasvand F, Parker D. Biochemistry of exercise-induced metabolic acidosis. Am J Physiol Regul Integr Comp Physiol 2004; 287: R502-16.

, cCrea

Creatinine

Creatinine is an endogenous waste product of muscle metabolism, derived from creatine, a molecule of major importance for energy production within muscle cells. Creatinine is removed from the body in urine and its concentration in blood reflects glomerular filtration and thereby kidney function.

Read more

Electrolytes: 
cCa2+

Calcium

The calcium ion (Ca2+) is one of the most prevalent cations in the body, where approximately 1 % is present in the extracellular fluid of blood. Ca2+ plays a vital role for bone mineralization and many cellular processes, e.g. contractility of the heart and the skeletal musculature, neuromuscular transmission, hormone secretion and action in various enzymatic reactions such as, e.g. blood coagulation.

Read more

, cCl-

Chloride

Chloride (Cl-) is the major anion in the extracellular fluid and one of the most important anions in blood. The main function of Cl- is to maintain osmotic pressure, fluid balance, muscular activity, ionic neutrality in plasma, and help elucidate the cause of acid-base disturbances.

Read more

, cK+

Potassium

Potassium (K+) is the major cation in the intracellular fluid, where it has a 25 - 37-fold higher concentration (∼150 mmol/L in tissue cells, ∼105 mmol/L in erythrocytes) than in the extracellular fluid (∼4 mmol/L) [1, 2]. K+ has several vital functions in the body, e.g. regulation of neuromuscular excitability, regulation of heart rhythm, regulation of intracellular and extracellular volume and acid-base status.

Read more

 

1. Burtis CA, Ashwood ER, Bruns DE. Tietz textbook of clinical chemistry and molecular diagnostics. 5th ed. St. Louis: Saunders Elsevier, 2012. Engquist A. Fluids/Electrolytes/Nutrition. 1st ed. Copenhagen: Munksgaard, 1985.
2. Engquist A. Fluids/Electrolytes/Nutrition. 1st ed. Copenhagen: Munksgaard, 1985.

, cNa+

Sodium

Sodium (Na+) is the dominant cation in the extracellular fluid, where it has a 14-fold higher concentration (∼140 mmol/L) than in the intracellular fluid (∼10 mmol/L). Na+ is a major contributor of the osmolality of the extracellular fluid and its main function is largely in controlling and regulating water balance, and maintaining blood pressure. Na+ is also important for transmitting nerve impulses and activating muscle concretion.

Read more

Oximetry: 
COHb

Carboxyhemoglobin

FMetHb is the fraction of total hemoglobin (ctHb) that is present as methemoglobin (MetHb). By convention the fraction is expressed as a percentage (%).

In the range of 0 – 60 % COHb in arterial (COHb(a)) and venous blood (COHb(v)) is similar, i.e. either venous or arterial blood may be analyzed [1]. In most medical texts FCOHb(a) is referred to as simply COHb.

Read more

 

1. Lopez DM, Weingarten-Arams JS, Singer LP, Conway EE Jr. Relationship between arterial, mixed venous and internal jugular carboxyhemoglobin concentrations at low, medium and high concentrations in a piglet model of carbon monoxide toxicity. Crit Care Med 2000; 28: 1998-2001.

, ctBil

Bilirubin

Bilirubin is the yellow breakdown product of the degradation of the heme group of hemoglobin. It is transported in blood from its site of production – the reticuloendothelial system – to the liver, where it is biotransformed before excretion in bile. Jaundice, the pathological yellow discoloration of skin, is due to abnormal accumulation of bilirubin in the tissues, and is always associated with elevated blood concentration of bilirubin (hyperbilirubinemia).

Read more

, ctHb

Total hemoglobin

The concentration of total hemoglobin (ctHb) in blood includes oxyhemoglobin (cO2Hb), deoxyhemoglobin (cHHb), as well as the dysfunctional hemoglobin species that are incapable of binding oxygen:

carboxyhemoglobin (cCOHb) (see COHb), methemoglobin (cMetHb) (see MetHb) and sulfhemoglobin (cSulfHb).

Thus:

ctHb = cO2Hb + cHHb + cCOHb + cMetHb + cSulfHb

The rare sulfHb is not included in the reported c tHb in most oximeters.

Read more

, FHbF

Fraction of fetal hemoglobin


FHbF in total hemoglobin in blood.

, FHHb

Fraction of deoxyhemoglobin


FHHb in total hemoglobin in blood.

, MetHb

Methemoglobin

FMetHb is the fraction of total hemoglobin (ctHb) that is present as methemoglobin (MetHb). By convention the fraction is expressed as a percentage (%) [1].

In most medical text boxes MetHb(a) is referred to as simply methemoglobin (MetHb).

Read more

 

1. CLSI. Blood gas and pH analysis and related measurements; Approved Guidelines. CLSI document CA46-A2, 29, 8. Clinical and Laboratory Standards Institute, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2009.

, sO2

Oxygen saturation

Oxygen saturation (sO2) is the ratio of oxyhemoglobin concentration to concentration of functional hemoglobin (i.e. oxyhemoglobin (O2Hb) and deoxyhemoglobin (HHb) capable of carrying oxygen [1].

The sO2 reflects utilization of the currently available oxygen transport capacity.

In arterial blood 98 – 99 % of oxygen is transported in erythrocytes bound to hemoglobin. The remaining 1–2 % of the oxygen transported in blood is dissolved in the blood plasma – this is the portion reported as partial pressure of oxygen (pO2) [2].

Read more

 

1. CLSI. Blood gas and pH analysis and related measurements; Approved Guidelines. CLSI document CA46-A2, 29, 8. Clinical and Laboratory Standards Institute, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2009.
2. Higgins C. Parameters that reflect the carbon dioxide content of blood. www.acutecaretesting.org Oct 2008.

, FO2Hb

Fraction of oxyhemoglobin

FO2Hb in total hemoglobin in blood.

Read more

Close

The equipment I use in my work must be trustworthy, user-friendly and reliable […] For more than ten years, we’ve been using the ABL800 series from Radiometer. It works very well for us.

- Anna-Karin Ståhlberg, Biomedical Analyst, Clinical Chemistry Laboratory, Halland´s Hospital Halmstad, Sweden

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How can we help you facilitate Seamless Diagnostics?

Support sample integrity with automatic mixing

Enable more accurate hemoglobin results with FLEXQ and safePICO syringes

Achieve reliable results from low volume samples

Leverage FLEXMODE and MICROMODE for results from samples of just 35μL

Select the parameters you use in practice

Customize analyzers to measure the parameters suited to your clinical practice

Built-in cybersecurity

Help protect patient data, reduce the risk of cyberattacks and consequent disruption to analyzer operation

Save time with FLEXQ's Drop-n-Go

Use safePICO syringes with FLEXQ for hands-free analysis of up to three successive samples

Reduce patient-sample mix up

Ensure correct patient-sample identification every time and improve workflow with 1st Automatic
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Confidently meet health care challenges with a trusted analyzer

The ABL800 FLEX is a reference point for blood gas testing and has specific features designed to:

  • Support sample integrity
  • Mitigate the influence of potentially interfering substances on co-oximetry and creatinine
  • Provide reliable results using dedicated measuring modes

Supporting an improved blood gas workflow with efficient automation

Drop-n-Go helps you reclaim time previously spent in front of the analyzer. Place up to three safePICO syringes on the FLEXQ and you're free to Go. Your samples will be scanned, mixed, aspirated, analyzed and reported, automatically.


Combine your ABL800 FLEX and safePICO syringes with AQURE's FLEXLINK system to utilize 1st Automatic. The connected solution registers patient, operator and sample IDs at the bedside, while FLEXLINK links these data together. An example of how it could expedite your workflow is shown below.

Improve your blood gas workflow with automation and connected solutions

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​

A flexible partner in meeting your needs

The ABL800 FLEX supports fluctuating blood gas testing demands with individual and replaceable consumables. The analyzer is adaptable, so you can customize it to meet your specific parameter and configuration needs.

To find out more, contact your local Radiometer representative. We're here to support you in constructing your unique setup.

Built-in cybersecurity helps increase uptime

The ABL800 FLEX has built-in cybersecurity features to help secure patient data and reduce the risk of cyberattacks and any consequent disruption to analyzer operation.

Our cybersecurity model operates as a multi-layered defense system, alongside hospital security measures. Based on Microsoft-supported operating systems, our proactive model includes Application Control, Patch management and system updates tested prior installation. Visit our Security Packages to learn more.

Experience the Power of Seamless Diagnostics

Blood gas syringes and capillary tubes

Meet your blood sampling needs with our samplers, designed to facilitate reliable test results 
More information

Centralized control with AQURE

AQURE provides you with a complete overview and access to manage the performance of your point-of-care and lab testing setup. Learn more about how AQURE can work for you.
More information

Integrated POC IT and Services

Connect & Care, a customizable, total solution that connects and supports medical devices, data, and people to keep your POC testing setup running smoothly.
More information
Download the Acute Care Testing Handbook

The acute care testing handbook

Download the free guide on blood gases and other critical parameters in acute care testing.

Download now

Let us help you prevent preanalytical errors

Find out more about the most common preanalytical errors and how to prevent them.
Read more

Guiding your blood gas testing

Through three educational videos, you’ll experience why blood gas analysis is important in three critical patient cases covering COPD, intoxication and sepsis. Further, a set of three how-to videos will guide you in performing an arterial puncture, understanding the acid-base balance in the blood and to reading the blood gas report.
Watch the blood gas tutorial videos
MAPSSS-000936 R1

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